High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, an 20,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.



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Cluster Utilization
Friday, February 23rd, 2018
utilization graph
Last 24 hrs
106,039 jobs submitted
81,267 jobs completed
2,426,608 CPU hrs used
23 NIH Institutes
177 Principal Investigators
313 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper Ridding fMRI data of motion-related influences: Removal of signals with distinct spatial and physical bases in multiecho data
Power, JD; Plitt, M; Gotts, SJ et al.
Proc. Natl. Acad. Sci. U.S.A. , DOI://10.1073/pnas.1720985115 (2018)

thumbnail image from paper The Antimicrobial Peptide CRAMP Is Essential for Colon Homeostasis by Maintaining Microbiota Balance
Yoshimura, T; McLean, MH; Dzutsev, AK et al.
J. Immunol. , DOI://10.4049/jimmunol.1602073 (2018)

thumbnail image from paper Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of Bacterial Plasmids Conferring Carbapenem Resistance
Weingarten, RA; Johnson, RC; Conlan, S et al.
MBio , DOI://10.1128/mBio.02011-17 (2018)

thumbnail image from paper Raf-1 Cysteine-Rich Domain Increases the Affinity of K-Ras/Raf at the Membrane, Promoting MAPK Signaling
Li, S; Jang, H; Zhang, J; Nussinov, R;
Structure , DOI://10.1016/j.str.2018.01.011 (2018)

thumbnail image from paper 5-Azacytidine prevents relapse and produces long-term complete remissions in leukemia xenografts treated with Moxetumomab pasudotox
Müller, F; Cunningham, T; Stookey, S et al.
Proc. Natl. Acad. Sci. U.S.A. , DOI://10.1073/pnas.1714512115 (2018)

thumbnail image from paper Global changes of H3K27me3 domains and Polycomb group protein distribution in the absence of recruiters Spps or Pho
Brown, JL; Sun, MA; Kassis, JA;
Proc. Natl. Acad. Sci. U.S.A. , DOI://10.1073/pnas.1716299115 (2018)

thumbnail image from paper Precise genome-wide mapping of single nucleosomes and linkers in vivo
Chereji, RV; Ramachandran, S; Bryson, TD; Henikoff, S;
Genome Biol. , DOI://10.1186/s13059-018-1398-0 (2018)