High-Performance Computing at the NIH
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The NIH HPC group plans, manages and supports high-performance computing systems specifically for the intramural NIH community. These systems include Biowulf, an 20,000+ processor Linux cluster; Helix, an interactive system for short jobs, Sciware, a set of applications for desktops, and Helixweb, which provides a number of web-based scientific tools. We provide access to a wide range of computational applications for genomics, molecular and structural biology, mathematical and graphical analysis, image analysis, and other scientific fields.



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Cluster Utilization
Tuesday, August 21st, 2018
utilization graph
Last 24 hrs
126,139 jobs submitted
81,663 jobs completed
2,802,738 CPU hrs used
24 NIH Institutes
177 Principal Investigators
307 users

Announcements
Recent Papers that used Biowulf & HPC Resources

thumbnail image from paper A coevolution-guided model for the rotor of the bacterial flagellar motor
Khan, S; Guo, TW; Misra, S;
Sci Rep , DOI://10.1038/s41598-018-30293-0 (2018)

thumbnail image from paper Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles
Liao, TJ; Jang, H; Fushman, D; Nussinov, R;
Biophys. J. , DOI://10.1016/j.bpj.2018.07.016 (2018)

thumbnail image from paper A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans
Tsai, PF; Dell'Orso, S; Rodriguez, J et al.
Mol. Cell , DOI://10.1016/j.molcel.2018.06.008 (2018)

thumbnail image from paper Re-analysis of Whole Genome Sequence Data From 279 Ancient Eurasians Reveals Substantial Ancestral Heterogeneity
Shriner, D
Front Genet , DOI://10.3389/fgene.2018.00268 (2018)

thumbnail image from paper A multiprotein supercomplex controlling oncogenic signalling in lymphoma
Phelan, JD; Young, RM; Webster, DE et al.
Nature , DOI://10.1038/s41586-018-0290-0 (2018)

thumbnail image from paper Effects of Human Sex Chromosome Dosage on Spatial Chromosome Organization
Jowhar, Z; Shachar, S; Gudla, PR et al.
Mol. Biol. Cell , DOI://10.1091/mbc.E18-06-0359 (2018)

thumbnail image from paper Glutamatergic Signaling Drives Ketamine-Mediated Response in Depression: Evidence from Dynamic Causal Modeling
Gilbert, JR; Yarrington, JS; Wills, KE; Nugent, AC; Zarate, CA;
Int. J. Neuropsychopharmacol. , DOI://10.1093/ijnp/pyy041 (2018)