High-Performance Computing at the NIH

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Solar on Helix
SOLAR is a package of software to perform several kinds of statistical genetic analysis, including linkage analysis, quantitative genetic analysis, and covariate screening. The name SOLAR stands for "Sequential Oligogenic Linkage Analysis Routines." Solar was developed by researchers at the Southwest Foundation for Biomedical Research.

New Solar users should send email to staff@helix.nih.gov asking to be registered as a Solar user. The Solar package requires each user to be registered.

If you expect to run more than 5 simultaneous Solar jobs, please use Solar on Biowulf

Running a Solar job

Once you have been registered as a Solar user, you can run Solar by typing 'module load solar' (once per session) and then 'solar' at the Helix prompt.

Sample session (user input in bold):

helix% module load solar             (will load the latest available version)

helix% module list                   (to show which version has been loaded)
Currently Loaded Modulefiles:
  1) solar/6.6.2

helix%$ solar

SOLAR version 6.6.2 (Official), last updated on December 07, 2012
Copyright (c) 1995-2012 Texas Biomedical Research Institute
Enter help for help, exit to exit, doc to browse documentation.

solar> load pedigree plains_ped.txt
Unloading current pedigree data ...
Unloading current marker data ...
Loading pedigree data from the file plains_ped.txt ...
solar> verbosity min
solar> freq mle
Marker data have not been loaded.
solar> load marker plainschr16_mrk.txt
Getting initial estimates of allele freqs from the marker data ...
Loading marker data from the file plainschr16_mrk.txt ...
solar> load map plainschr16_map.txt
solar> mibd prep loki
Preparing input files for Loki multipoint IBD computation ...
The following files have been created:
    lkmibd.data         - pedigree/genotype data
    lkmibd.prep         - prep parameter file
    lkmibd.loki         - loki parameter file
    mibdchr16.loc       - map file for SOLAR plots
Move the file mibdchr16.loc to the directory where the Loki-computed IBDs
will be stored.

[...etc...]

solar> quit

helix%

Documentation

Solar 6.6.2 documentation

Solar documentation at the SFBR website.