High-Performance Computing at the NIH

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BEAST

Description

BEAST (Bayesian Evolutionary Analysis Sampling Trees) is a cross-platform program for Bayesian MCMC analysis of molecular sequences. It is entirely orientated towards rooted, time-measured phylogenies inferred using strict or relaxed molecular clock models. It can be used as a method of reconstructing phylogenies but is also a framework for testing evolutionary hypotheses without conditioning on a single tree topology. BEAST uses MCMC to average over tree space, so that each tree is weighted proportional to its posterior probability. We include a simple to use user-interface program for setting up standard analyses and a suit of programs for analysing the results.

How to Use

Please set your environment using environment modules:

module load BEAST

Older versions can be found using the command

module avail BEAST

Once your environment is set, then simply run a command. Here is a simple example:

cp $BEAST_EXAMPLES/Benchmarks/benchmark1.xml .
beast benchmark1.xml

Documentation