Scientific Supercomputing at the NIH
The Helix Systems group is responsible for the planning and management of high-performance computing systems specifically for the intramural NIH community. These systems include Helix, a multiprocessor shared-memory system for interactive use; Biowulf, a 6300+ processor Linux cluster; and Helixweb, which provides a number of scientific tools via the web. We provide access to a wide range of computational applications for molecular and structural biology, mathematical and graphical analysis, and other scientific fields.



Recent Publications Citing Helix and Biowulf:

A molecular dynamics study of the structure and inter-particle interactions of polyethylene glycol-conjugated PAMAM dendrimers
Hwankyu Lee and Ronald G. Larson
J. Phys. Chem. B 113(40) :13202-13207 (2009)

NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif
Yuki Kuwano, Rudolf Pullmann, Jr., Bernard S. Marasa, Kotb Abdelmohsen, Eun Kyung Lee, Xiaoling Yang, Jennifer L. Martindale, Ming Zhan and Myriam Gorospe
Nucleic Acids Research , published online 22 Oct (2009)

Thermodynamic Perspective on the Dock Lock Growth Mechanism of Amyloid Fibrils
Edward P. O'Brien, Yuko Okamoto, John E. Straub, Bernard R. Brooks and D. Thirumalai
J. Phys. Chem. B 113(43) :14421-14430 (2009)

MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival
Ewy A. Mathè, Giang Huong Nguyen, Elise D. Bowman, Yiqiang Zhao, Anuradha Budhu, Aaron J. Schetter, Rosemary Braun, Mark Reimers, Kensuke Kumamoto, Duncan Hughes, Nasser K. Altorki, Alan G. Casson, Chang-Gong Liu, Xin Wei Wang, Nozomu Yanaihara, Nobutoshi Hagiwara, Andrew J. Dannenberg, Masao Miyashita, Carlo M. Croce and Curtis C. Harris
Clin. Cancer. Res. 15 :6192 (2009)