High-Performance Computing at the NIH
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The Helix Systems group is responsible for the planning and management of high-performance computing systems specifically for the intramural NIH community. These systems include Helix, a multiprocessor shared-memory system for interactive use; Biowulf, a 12,000+ processor Linux cluster; and Helixweb, which provides a number of scientific tools via the web. We provide access to a wide range of computational applications for molecular and structural biology, mathematical and graphical analysis, and other scientific fields.



Recent Publications Citing Helix and Biowulf:

thumbnail image from paper A Genome-wide Map of CTCF Multivalency Redefines the CTCF Code
Hirotaka Nakahashi, Kyong-Rim Kieffer Kwon, Wolfgang Resch, Laura Vian, Marei Dose, Diana Stavreva, Ofir Hakim, Nathanael Pruett, Steevenson Nelson, Arito Yamane, Jason Qian, Wendy Dubois, Scott Welsh, Robert D. Phair, B. Franklin Pugh, Victor Lobanenkov, Gordon L. Hager, and Rafael Casellas
Cell Reports , doi://10.1016/j.celrep.2013.04.024 (2013)

thumbnail image from paper Global Regulation of Promoter Melting in Naive Lymphocytes
Fedor Kouzine, Damian Wojtowicz, Arito Yamane, Wolfgang Resch, Kyong-Rim Kieffer-Kwon, Russell Bandle, Steevenson Nelson, Hirotaka Nakahashi, Parirokh Awasthi, Lionel Feigenbaum, Herve Menoni, Jan Hoeijmakers, Wim Vermeulen, Hui Ge, Teresa M. Przytycka, David Levens, and Rafael Casellas
Cell 153(5) :988-999, doi://10.1016/j.cell.2013.04.033 (2013)

thumbnail image from paper A 5′-Flanking Region of Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) Gene Directs Its Cell-Specific Androgen-Regulated Gene Expression in Testicular Germ Cells
Raghuveer Kavarthapu, Chon-Hwa Tsai-Morris, Masato Fukushima, James Pickel and Maria L. Dufau
Endocrinology , doi: 10.1210/en.2012-2230 (2013)

thumbnail image from paper Improving Peptide Identification Sensitivity in Shotgun Proteomics by Stratification of Search Space
Gelio Alves and Yi-Kuo Yu
J. Proteome Research , DOI: 10.1021/pr301139y (2013)